Research Grant Awards

The AOFAS Research Grants Program is supported by the Orthopaedic Foot & Ankle Foundation with generous contributions from individuals and industry. Grant applications are reviewed and ranked by the Research Committee using a blinded NIH-style review process and funding recommendations are approved by the AOFAS Board of Directors. For information on applying for a grant, please visit the Research Grants Program page.


​   Funded Project Category & Title

2018 Pilot Project Research Grant
Development of Best Practices Guidelines for Pain Management After Elective Foot and Ankle Surgery 
Mary Pedersen, MD; Derek Dillane, PhD; Lauren Beaupre, PhD; Martha Funabashi, PhD 
​2018 Pilot Project Research Grant
The Effect of Bone Marrow Aspirate Concentrate with Microfracture: A Prospective Randomized Control Trial 
John Mangan, MD; Rachel Shakked, MD; Joseph Daniel, DO; David Pedowitz, MD; Brian Winters, MD; Steven Raikin, MD
​2018 Pilot Project Research Grant
The Effectiveness of Perioperative Parecoxib Intravenous Administration in the Patients with Unstable Ankle Fractures Surgery: A Prospective, Double-blinded, Randomized, Placebo-Controlled Trial 
Chayanin Angthong, MD
2018 Small Project Research Grant
Predicting Collagen Turnover for Achilles Tendon Repair Across Diverse Loading Environments 
Christopher Gross, MD; William Richardson, PhD
2018 Small Project Research Grant
3D Motion Analysis of Adjacent Joint Motion After Sequential, Partial Midfoot Infusion 
Lauren Roberts, MD; Mark Drakos, MD; Daniel Sturnick, MS; Scott Ellis, MD
2018 Small Project Research Grant
Applying Machine Learning Algorithms to Predict Tendon Health Using Ultrasound Imaging 
Josh Baxter; Kathryn O’Connor, MD, MSPT; Michael Hast, PhD 
2018 Established Project Research Grant
The Neuropathic Molecular Pathology of Diabetic Charcot Neuroarthropathy: A Peptidomic Investigation of the Synovium 
Zijun Zhang, MD; Lew Schon, MD; Robert Cole, PhD 
2017 Pilot Project Research Grant
Assessment o​f the Prevalence and Safety of Left Foot Driving in Right Foot and Ankle Surgery Patients
Michael D. Johnson, MD; Despina Stavrinos, PhD​; Ashish B. Shah, MD; Ibukunoluwa B. Araoye, MS; Parke W. Hudson, BS​
2017 Small Project Research Grant
Regional Epigenetic Responses of a Human Talar Cartilage to Impact Injury: An Investigation into Mechanisms of Post Traumatic Ankle Arthritis
Amiethab A. Aiyer, MD; Chun-Yuh Huang, PhD; Jonathan R.M. Kaplan, MD; Anish R. Kadakia, MD; Spencer Summers, MD; Hayley Ennis, MD​
2017 Small Project Research Grant
The Role of the Syndesmosis in Ankle Joint and Tibiofibular Kinematics
MaCalus V. Hogan, MD; Conor I. Murphy, MD; Richard E. Debski, PhD; Volker Musahl, MD
2017 Small Project Research Grant
The Role of the Lateral Structures in Controlling Laxity of the Ankle Joint and the Ability of the Brostrom-Gould Reconstruction to Restore Native Joint Kinematics: A Biomechanical Investigation
James D.F. Calder PhD, FRCS; Hadi ElDaou, PhD
2017 Small Project Research Grant
Development of a Method to Diagnose Subtle Syndesmosis Instability
Alexej Barg, MD; Charles L. Saltzman, MD
2017 Established Project Research Grant
Defining the Cellular Basis for Poor Muscle Performance in Diabetic Peripheral Neuropathy​
Gretchen A. Meyer, PhD; Jeffrey E. Johnson, MD; Sandra E. Klein, MD; Jeremy J. McCormick, MD; David R. Sinacore, PT, PhD
2016 Pilot Project Research Grant
Do Knee Scooters Contribute to Lower Extremity Venous Stasis?
Christopher W. Reb, DO; Gregory C. Berlet, MD
​2016 ​Pilot Project Research Grant
Development of a Real Time Model of Foot and Ankle Kinematics During Simulated Gait – A Pilot Study
Bryan Smith, MD; Michael S. Pinzur, MD; Robert M. Havey, MS; Muturi G. Muriuki, PhD; Adam P. Schiff, MD
​2016 Small Project Research Grant
A Prospective Analysis of Midfoot Function, Ankle Power and Patient Functional Outcomes After Total Ankle Arthroplasty
Frank DiLiberto, PT, PhD; Steven L. Haddad, MD; Anand M. Vora, MD
2016​​ Small Project Research Grant
Evaluation of Local Vancomycin Powder on Osteoblastic Function and Healing in a Rodent Ankle Arthrodesis Model
Jason T. Bariteau, MD; Rishin J. Kadakia, MD; Mara L. Schenker, MD; Nick J. Willet, PhD
​2016 Small Project Research Grant
Arthroscopic Evaluation of the Ankle Syndesmosis: A Cadaveric Study
Christopher W. DiGiovanni, MD; Bart Lubberts, MD; Bryan G.Vopat, MD; Anne H. Johnson, MD; Daniel Guss, MS, MBA
2016 ​Established Project Research Grant
Supramalleolar Osteotomy: Mid- to Long-Term Results of 298 Consecutive Patients
Nicola Krähenbühl, MD; Lukas Zwicky, MSc; Liliana Bolliger, MSc; Markus Knupp, MD
​2016 Established Project Research Grant
In Vitro Assessment of the Role of Mechanical Strain in the Pathogenesis and Reversal of Insertional Achilles Tendinopathy
Mark R. Buckley, PhD; Adolph S. Flemister, Jr., MD; Alayna E. Loiselle, PhD; Michael S. Richards, PhD
​2015 Pilot Project Research Grant
Methodology for the Videao Analysis of Surgical Performance in Orthopedic Ankle Surgery
Douglas Beaman, MD
2015 The Effect of Hindfoot Deformity on the Ankle Utilizing a Novel System to Simulate Weight Bearing in a Cadaveric Model
Naven Duggal, MD and Ara Nazarian, PhD
2015 Arthroscopic Talar and Plafond Access for Osteochondral Lesions: The Effect of Limited Ankle Range of Motion on CT-Predicted Accessibility and Arthroscopic Visualization
Craig Chike Akoh, MD, Phinit Phisitkul, MD, and Annunziato Amendola, MD
2015 Differences in Gait After Ankle Arthrodesis and Ankle Arthroplasty When Ascending and Descending Stairs
Constantine Demetracopoulos, MD and Howard Hillstrom,  PhD
2015 Restoration of the Antibacterial Function of Mesenchymal Stem Cells in Diabetic Foot Infection
Zijun Zhang, PhD, MD and Lew Schon, MD
2015 Direct Delivery of Bone Morphogenetic Protein-2 and Fibroblast Growth Factor-2 Plasmid Genes for Diabetic Fracture Healing in a Rabbit Model
Nathan Nicholson, MD, John Femino, MD, and Alisager Salem, PhD
2014 Ankle Arthroscopic Simulation Decreases Surgical Error and Improves Basic Arthroscopic Skills of Residents in Training
Kevin Martin, DO; Phinit Phisitkul, MD; John Femino, MD; and Annunziato Amendola, MD
2014 Enhancement of Achilles Tendon Repair via Peripheral Blood Mobilization and Chemokine-Dire​​​​​cted Migration of Native Marrow-Derived Stem Cells
Kevin Baker, PhD and Paul Fortin, MD
2014 Prospective Comparison of the NIH PROMIS Physical Function, Lower Extremity, and Pain --  Interference CATs Against the Foot and Ankle Outcome Score and SF-12 for Patients with Common Foot and Ankle Conditions
Stephen Greenfield, MD; Scott Ellis, MD; Hong Do, MS; and Jayme Burket, PhD
2014 In-vivo Arthrokinematics and Kinetics in the Normal and Chronically Unstable Ankle 
Charles Saltzman, MD and Andrew Anderson, PhD 
2013 Syndesmotic distruption: Changes in tibiofibular motion and ankle contact stresses
Mark Drakos, MD, Jeremy La Mothe, MD; Josh Baxter, PhD
2013 A biomechanical comparison of a novel spring ligament reconstruction technique with previously reported techniques
Josh Baxter, PhD; Jonathan T. Deland, MD
2013 Syndesmotic disruption:  changes in tibiofubular motion and ankle contact stresses
Mark C. Drakos, MD; Jeremy LaMothe, MD; Josh Baxter, PhD
2013 Adipogenesis of adipose tissue derived mesenchymal stem cells in foot fat pad
Zijun Zhang, MD; Lew Schon, MD
2012 Ankle joint pressure in pes cavus after lateralizing supramalleolar and calcaneal osteotomy
Timo Schmid, MD; Fabian Krause, MD
​Exercise effect on diabetic (db/db) mice Achilles tendons
Robert Laughlin, MD; Greg Boivin, DVM
​2012 Radiographic evaluation of plantar plate injury: An invitro biomechanical study
Thomas Clanton, MD; Norman Waldrop, III, MD
2012 Clinical and biomechanical outcomes following gastrocnemius recession vs plantar fasciotomy for plantar fasciitis:  A prosective randomized controlled clinical tool
Erik Nilssen, MD; Elizabeth Russell, PhD
The effect of a bisphosphonate pretreatment on the enhancement of osseous incorporation and chondrocyte viability of fresh osteochondral allografts
Paul T. Fortin, MD; Kevin Baker, MS
Proprioception and neuromuscular control following ankle instability surgery
Gregory Gutierrez, PhD; Kenneth J. Mroczek, MD
Early vs delayed weight-bearing after microfracture for osteochondral lesions of the talus
Kevin L. Kirk, DO; James R. Ficke, MD
Biomechanical factors impacting foot function and muscle performance following gastrocnemius recession
Deborah Nawoczenski, PhD, PT; Benedict F. DiGiovanni, MD
Metabolic profiling and cytokine analysis of synovial fluid in healthy and end-stage post-traumatic ankle joints
Samuel B. Adams, MD; Lew C. Schon, MD
Gastrocnemius recession versus Achilles tendon debridement with flexor hallucis longus transfer for chronic noninsertional Achilles tendinopathy: A prospective randomized controlled trial
John G. Anderson, MD; Donald R. Bohay, MD
Three-dimensional non-invasive kenematic analysis of the transverse tarsal joint and determination of the role of the plantar fascia on the transverse tarsal locking mechanism
Brad Blankenhorn, MD; Christopher W. DiGiovanni, MD
In-vivo comparison of plantar pressures in pes rectus, pes planus, and the adult acquired flatfoot using supine, vertical posture, and gait measurements
Scott J. Ellis, MD; Howard Hillstrom, PhD
Investigation into genome-wide differential expression between diabetic and non-diabetic patients in healing of ankle fractures
Lorenzo Gamez, MD; Brian Silvia, MD
Plantar pressure analysis in forefoot after different amount of lateral column lengthening: A biomechanical study
Jonathan T. Deland, MD; Irvin Oh, MD
The biomechanics of cartilage damage and repair at the ankle joint
John G. Kennedy, MD; Carl W. Imhauser, PhD; Padhraig F. O’Loughlin, MD
Ankle joint pressure in pes cavus after common hindfoot osteotomies
Fabian Krause, MD; Karsten Schwieger, PhD
Effectiveness of Morton’s extension carbon foot plate in the non-operative treatment of hallux rigidus
Amar Patel, MD; Judith F. Baumhauer, MD; Deborah Nawoczenski, PhD, PT
A biomechanical analysis of a tensioned suture device in the fixation of a ligamentous Lisfranc injury
Timothy C. Beals, MD; Chris Pelt, MD
Early surgical treatment of displaced intra-articular calcaneus fractures through a combined medial and lateral approach
Wayne S. Berberian, MD; Frank Liporace, MD
Can human bone marrow-derived stem cells differentiate into tendon-forming cells?
Nicholas Forsyth, PhD; Nicola Maffulli, MD
Lower extremity kinetics and kinematics during stair climbing
in patients with ankle osteoarthritis
Tricia Hubbard, PhD, ATC; Robert B. Anderson, MD
Stiffness and histology analysis of the ankle joint cartilage
Victor Valderrabano, MD, PhD; Olaf Buettner, MD
Canadian Orthopaedic Foot and Ankle Society (COFAS) multi-centered randomized case controlled trial on clinical and radiographic outcome of total ankle arthroplasty vs. ankle ankle arthrodesis
Mark A. Glazebrook, MD; Timothy R. Daniels, MD; Alastair Younger, MD
The intraosseous innervation of the talar dome: A histologic study
Sandra E. Klein, MD; John V. Marymont, MD; Francis H. Gannon, MD; Kevin E. Varner, MD
Load Transfer in Transtibial Amputation with Distal Tibio-Fibular Bond Bridging
Michael S. Pinzur, MD; Avinash Patwardhan, PhD
Enhancing conservative management of patients with midfoot arthritis
Smita Rao, PhD, PT; Benedict F. DiGiovanni, MD; Deborah Nawoczenski, PhD, PT
Development of a method to quantify subtalar joint instability
Stacie Ringleb, PhD; Claude D. Anderson, MD; Marlene DeMaio, MD
Quantitative and qualitative description: Effects of bone marrow derived growth factors and cytokines on autogenous mesenchymal stem cells of various aspiration sites
Lew C. Schon, MD; Su-Young Bae, MD, PhD; Stuart D. Miller, MD
The effect of continuous irrigation during burring on thermal necrosis and fusion strength in rabbit arthrodesis model
Steven L. Haddad, MD; Cary Templin, MD
Effect of Bracing and strengthening exercise on foot kinematics and functionin subjects with stage II PTTD
Jeffrey Houck, PhD, PT; Judith F. Baumhauer, MD
Second and third MT stress fracture: gender, kinematics, kinetics and plantar plate difference as they relate to stress fracture
Robin Queen, PhD; James A. Nunley, MD
Inflammatory cytokines expression in degenerative tendonosisquantitative description and relation to whole tendon mechanical stimuli
Lew C. Schon, MD; Gregory P. Guyton, MD
The effect of medial calcaneal osteotomy and lateral column lengthening on forefoot pressures
Robert S. Adelaar, MD; Aaron T. Scott, MD; Travis M. Hendry, MD; Jennifer Wayne, PhD
Biomechanical and Anatomic Analysis of Minimally Invasive Deltoid Ligament Reconstruction
Eric M. Bluman, MD, PhD; Mark S. Myerson, MD
Hindfoot motion after reconstruction for posterior tibial tendon dysfunction
James W. Brodsky, MD; Fabian E. Pollo, PhD
Ankle arthrodesis vs. Ankle arthoroplasty for End Stage ankle arthritis: a prospective functional comparison
Timothy R. Daniels, MD
A randomized controlled trial of 1st MTP joint fusion compared to 1st MTP hemiarthroplasty in severe hallux rigidus
Johnny T.C. Lau, MD; Timothy R. Daniels, MD
Evaluation of the effect of preoperative varus and valgus knee alignment on postoperative foot and ankle alignment, function, and outcome after total knee replacement
Simon Lee, MD; George B. Holmes, Jr, MD; Johnny L. Lin, MD
Prospective randomized clinical pilot study to evaluate the effects of the medial distal locking plate for high energy intra-articular fracture of distal tibia
David J.G. Stephen, MD; Wade Gofton, MD
Strength of the Achilles Insertion Site After Partial Retrocalcaneal Exostectomy: A Biomechanical Study
Thomas O. Clanton, MD; Jeremy Britten, MD
The impact of Interleukin 17 on the Production of Nitric Oxide and Prostaglandin E2 in Normal and Osteoarthritic Human Ankle and Knee Cartilage
James A. Nunley, MD; Farshid Guilak, PhD
The Effect of Walking Speed on Forefoot Motion and Loading in Patients with Ankle Arthordesis or Arthoplasty
Charles L. Saltzman, MD; Jason M. Wilken, PhD, MPT
Augmentation of Achilles Tendon Healing Using Gene Therapy with BMP 14 in a Rat Model
Brian C. Toolan, MD; Rebecca A. Cerrato, MD; Rex Haydon, MD, PhD
The effect of intra-articular fractures on fractures on cartilage in humans
Michael E. Brage, MD; Scott T. Ball, MD; David Amiel, PhD
The additional stability achieved by adding the inferior extensor retinaculum tissue to the brostrom lateral ankle ligament reconstruction
Andrew J. Elliott, MD; James C. Otis, PhD
Investigation of midtarsal locking
William Ledoux, PhD; Bruce J. Sangeorzan, MD
Design and implementation of a prospective foot and ankle outcomes database
Nelson Fong SooHoo, MD
The role of the ankle articular surfaces in controlling joint motion
Yuki Tochigi, MD, PhD; Charles L. Saltzman, MD; J. James Rudert, PhD; Thomas D. Brown, PhD
MRI Evaluation of First Metatarsophalangeal Joint Kinematics
Judith F. Baumhauer, MD
Reliability and Validity of the American Orthopaedic Foot and Ankle Clinical Rating Scale
Judith F. Baumhauer, MD
Experimental Overuse Achilles Tendinopathy: Establishment and Histological Validation of a Rat Tendonosis Model with Characterization of Molecular Cross Linking, Collagen Types I and III, Biomechanical Properties and Effect of Mechanical Stress
Mark A. Glazebrook, MD
The Effect of Foot Orthoses on Posterior Tibialis, Tibialis Anterior, and Peroneus Longus Muscle Electromyographic Activity During Walking and Running
Michael P. Schaefer, MD
The Effect of Variation in Rocker Sole Design on Gait Characteristics and Planter Pressures with Walking in a Total Contact Cast
Jeffrey E. Johnson, MD
Ankle Joint Stability: Ligamentous and Articular Constraints
Kenton R. Kaufman, PhD; Kota Watanabe, MD; Harold B. Kitaoka, MD
The Effect of Achilles Tendon Stretching on Weightbearing
David S. Levine, MD; James C. Otis, PhD
Identification of Potential Donor Rotational Bone Grafts using Vascular Territories in the Foot and Ankle
James A. Nunley, MD
Kinematic Analysis of the Normal and Flatfoot Deformity
Rita M. Patterson, PhD
Tendon Transfer Fixation in the Foot and Ankle: Biomechanical Comparison of Traditional Fixation Versus Bioabsorbable Screw Fixation
Thomas O. Clanton, MD
Gastrocnemius Recession For The Correction Of Equinus Deformity in the Adult
Steven D. Steinlauf, MD
Normal Human Talonavicular Joint Kinematics in Gait
Anthony D. Watson, MD
Clinical Pathophysiology of Plantar Fasciitis
Nicholas A. Abidi, MD; Rocky S. Tuan, PhD
Comparative Biomechanical Analysis of Fusion Techniques for Tibiotalocalcaneal Arthrodesis
Jorge I. Acevedo, MD; Lew C. Schon, MD
Comparison of Plantar Pressure Changes and Foot Ulcer Healing Times in DM Patients Wearing TCC and Pneumatic Walking Brace
Sheldon S. Lin, MD; Gregory H. Sirounian, MD
Botulinum Toxin Injections for Prevention of Contracture in Augmentation of Tendon Repair
Eyal A. Melamed, MD; Mark S. Myerson, MD
Delayed Fracture Healing in Diabetes Mellitus BB Wistar Rats: Model and Potential Txt
Sheldon S. Lin, MD; J. Russell Parsons, PhD
Achilles Tendon Lengthening for Reduction of Forefoot Ulceration in the Diabetic Patient
Neil Sharkey, PhD; Paul J. Juliano, MD; Peter R. Cavanagh, PhD
Biomechanical Evaluation of Suture Anchor Strength for Reattachment of Achilles Insertion
Thom A. Tarquinio, MD; Douglas E. Parsell, PhD
The Effects of Adult Acquired Flatfoot Deformity on the Tibiotalar Joint Contact Characteristics
Michael E. Brage, MD; Louis F. Draganich, PhD
Biomechanics of Lisfranc Joint
Lisa T. DeGnore, MD
Biomechanical and Immunohistochemical Study of the MCL of the Big Toe MTP Joint
Zong-Ping Luo, PhD
Review of Technique and Demonstration of Experimental Flatfoot Model
Bruce J. Sangeorzan, MD